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Moreover, multi-organ autologous chip platforms could replicate critical inter-organ communication, allowing for a more complete understanding of systemic drug responses and adverse effects

cDNA was synthesized using the Revert Aid H Minus First Strand cDNA Synthesis Kit (Thermo Fisher Scientific) following the protocol, as given by the manufacturer

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We summarized the current evidence with reference to targeted gene and epigenome-wide association studies stratified by the level of evidence from high to very low